Background And Objective: Febrile convulsions are the most common type of seizures disorder in children. Febrile seizure is an event in infancy and early childhood usually occurring between 6 months and 5 years of age, associated with fever but without the evidence of intracranial infection or defined cause. The aim of the present prospective analytical case control study was to estimate the levels of serum zinc in children with febrile convulsions and to compare serum zinc levels between children with febrile seizures and febrile children without seizures
Materials And Methods: A comparative study was done on 100 children for one year period from August 2014 to July 2015, in Rajah Muthiah medical college & hospital, Chidambaram. Of these 50 children were diagnosed to have febrile convulsions. The other 50 were febrile children without seizures. Serum zinc levels were measured in all 100 subjects using calorimetric methods. Data was analyzed.
Results: Mean Serum zinc levels in children with febrile seizures were 68.4 micrograms/deciliter and mean serum zinc levels in control group was 94.1 micrograms/dl (p=0.0001).
Interpretation And Conclusion: These findings revealed that there is correlation between serum zinc and simple febrile seizures. Serum zinc level was significantly lower in children with simple febrile seizures in comparison with febrile children without seizure.