Guar gum hydrogel asdrug delivery controlled release system : review

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Author: 
Prisca Safriani Wicita., Anis Yohana Chairunisaa

Guar gum is one of the largest non-ionic polysaccharides present in nature and has many uses especially in drug delivery applications. Guar gum has high swelling characteristics in water, this limits the use of guar gum as a carrier for drug delivery. Therefore, in order to overcome this, modification can be done by grafting, derivatization, and tissue formation to improve the characteristics so that it can be used as an excipient with good potential release. Along with the development, guar gum and its derivatives are now available in the form of hydrogel, coating, tablet matrix, and nano/microparticles that can be utilized as potential carriers of targeted drug delivery. Several studies have shown that the use of modified guar gum hydrogels for controlled drug release drug functionality gives positive results. Example of application of guar gum hydrogel as a controlled release drug carrier such as a carrier for delivery of a drug targeted to the colon (colon specific controlled drug delivery carrier)

Page: 
440-443
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