A study of thyroid profile in abnormal uterine bleeding (aub) among reproductive age group women


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Komathi, R, Mallika A and Shantha

Introduction: Abnormal uterine bleeding is a common problem and its management can be complex. Thyroid hormones play a key role in the menstrual and reproductive function of women. It is recognized universally that menstrual disturbances may accompany clinical alterations in thyroid function. Both hypothyroidism and hyperthyroidism may result in menstrual disturbances. Since thyroid dysfunction is commonly prevalent in women, present study was conducted to assess the prevalence of thyroid disorders in abnormal uterine bleeding patients.
Aims and objectives
• To evaluate thyroid function tests in women with AUB.
• To study the correlation of hemoglobin with menstrual patterns in AUB
• To evaluate BMI in Thyroid Disorders
Material and methods
Study design: Hospital based Cross sectional study. Study area: Dept. of Obstetrics and Gynecology, Rajah Muthiah Medical College and Hospital, Annamalai University, Chidambaram – 608 002. Study period: 2 year
Materials: A predesigned and restructured questionnaire, routine blood investigation, trans-abdominal USG, serum T3, T4, TSH. Sample size: 100. Sampling: Systematic Random Sampling. Statistical Analysis: Analyzed using Epi-info version 3.5.2.
Results: Most of the AUB cases were in the age group of 30 - 45 years, (78%) followed by 21-30 years (13%) and 9% were in the age group of <20 years. Hypothyroidism was present in 27% and Hyperthyroidism in 3% of the women with AUB. Thyroid dysfunction was most common in women aged between 30 – 45 yrs i.e. (82%). The commonest menstrual complaint was menorrhagia which was present in 72% of the AUB cases. Hypothyroidism is found to have increased BMI whereas Hyperthyroidism has decreased BMI
Conclusions: Thyroid dysfunction is associated with menstrual disturbances (abnormal uterine bleeding). Prevalence of hypothyroidism was more common than hyperthyroidism in AUB cases. Thyroid function tests should be performed in all patients with menstrual irregularities (AUB) to avoid unnecessary interventions. BMI and hemoglobin have a significant association with thyroid disorders and AUB respectively

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