The mehran risk scoring system for predicting contrast induced nephropathy following percutaneous coronary intervention: stronger positive correlation in the indian scenario

K Sivaprasad., Mathew Iype., Sanjai Pattu Valappil., Sunitha Viswanathan and A .George Koshy

Objective: To study the applicability and predictability of the Mehran risk score (MRS) in the prediction of Contrast Induced Nephropathy (CIN) in the Indian population.

Methods: This was a prospective observational study where high risk patients with estimated glomerular filtration rate (eGFR) between 30 -60 ml/mt under going elective percutaneous coronary intervention (PCI) were evaluated prospectively for the development of CIN. The high risk patients who developed CIN were then analysed for the presence of specific risk factors. All patients were assigned a baseline MRS and were categorised into the 4 risk groups based on the MRS.

Results: One hundred high risk patients underwent PCI during the study period. When the patients were analysed based on the MRS it was seen that with increasing MRS> 5, the observed incidence of CIN was substantially higher compared to the predicted risk for each category.

Conclusions: MRS is a useful in predicting the development of CIN in patients undergoing PCI. The incidence of CIN in high risk patients undergoing PCI is substantial. In an Indian population, higher MRS relegates these high risk patients to significantly higher risk of CIN compared to western population in which MRS was originally developed.

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