Dipsi - a single step procedure for screening and diagnosis of gestational diabetes mellitus

Keerthiha, B, Sangeereni, M and Mallika, A

Background: Indian women have eleven fold increased risk of developing glucose intolerance during pregnancy compared to Caucasian women. Universal screening for GDM is essential in India. However, the screening and diagnosis of gestational diabetes mellitus (GDM) continues to be a contentious issue. Notwithstanding decades of research and several international workshops devoted to GDM, there is still no consensus among international bodies on a uniform global approach for screening and diagnosis of GDM1. The lack of consensus regarding the screening and diagnostic criteria for GDM means that different sets of women would be identified as having GDM by the different criteria. The guidelines used depend on several factors like the availability of infrastructure, cost considerations and patient convenience. Poor dissemination of information and availability of resources could be some of the reasons for these conflicting guidelines used in different settings. This study was undertaken to find out a single step procedure which serves both as a screening and a diagnostic tool.
Methods: This study was carried out in a tertiary care teaching institute in Chidambaram.100 pregnant women with gestational age between 24-28 weeks were subjected to 75 grams OGTT recommended by DIPSI and venous blood sample was drawn after 2 hr.
Results: Out of 93 patients (7 subjects who developed GI intolerance were dropped out) 18 patients were diagnosed to have GDM (19.3%). Mean glucose value in GDM patients was 161.40 ± 28.05mg/dl whereas in Non GDM group it was 111.64 ± 12.03mg/dl with p value < 0.001 which is significant.
Conclusion: High prevalence of GDM may be because of high sensitivity of DIPSI. This method serves both as a screening and diagnostic procedure and is simple, reliable, feasible, easy to perform, economical especially in Indian settings.

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