Comparison of effectiveness of enoxaparin on maternal mortality and costafter elective and emergency cesarean section

Author: 
Servet Gencdal., Hüseyin Aydogmus., Nihan Gencdal., Emre Ekmekci., Zafer Kolsuz., H.Ibrahim Tıras and Serpil Aydogmus

Objective: Cesarean sections (CS) are believed to be associated with greater risks of postpartum venous thromboembolism (VTE). VTE remains one of the main direct causes of maternal mortality in developed countries, largely due to pulmonary thromboembolism (PE) which is responsible for around 20% of maternal deaths. The present study aimed to comparison of enoxaparin use for elective and emergency cesarean section on maternal mortality and cost effective in our hospital.
Material and Method: This study was conducted with 200 patients who underwent emergent or elective cesarean section in Izmir Katip Celebi University Atatürk Education and Research Hospital Obstetrics and Gynecology Clinic between 01.01.2016 and 01.01.2017 after the recommendation for venous tromboembolism in pregnancy which published from the ministry of health’s ‘guideline for the management of risky pregnancies’ in 2014. Enoxaparin was used to all patient for VTE prophylaxis in direction of recommendation the ministry of health’s guidelines.
Results: 100 patiens were elective CS and 100 patients were emergency CS. All patients mean age was 29.43±5.71 years, mean gestational was 38.22±1.61 weeks. Body mass index (BMI) was 29.88±4.7 kg/m2. There was no any venous thromboemboli and maternal mortality and morbidity in two groups. There were no statistically significant differences between the groups when compared to cost effectiveness.
Conclusion: This study shows safety and efficacy of enoxaparin for venous thromboprophylaxis after C/S. Although our study population are limited, but we agree with the recommendations of recent ministry of health’s guidelines.

Page: 
357-361
Download PDF: